A DRD2 and ANKK1 haplotype is associated with nicotine dependence
نویسندگان
چکیده
منابع مشابه
Haplotype analysis of DRD2 and ANKK1 gene polymorphisms in alcohol dependence
Jolanta Kucharska-Mazur1, Anna Grzywacz1, Justyna PełkaWysiecka1, Agnieszka samochowiec1,2, Hans Rommelspacher3, Jerzy samochowiec1: 1 Department of Psychiatry, Pomeranian Medical University, 26 Broniewskiego Str., 71-460 Szczecin, Poland. 2 Department of Clinical Psychology and Psychoprophylaxis, Institute of Psychology, University of Szczecin, 69 Krakowska Str., 71-004 Szczecin, Poland. 3 Dep...
متن کاملAssociations of Prenatal Nicotine Exposure and the Dopamine Related Genes ANKK1 and DRD2 to Verbal Language
Language impairment (LI) and reading disability (RD) are common pediatric neurobehavioral disorders that frequently co-occur, suggesting they share etiological determinants. Recently, our group identified prenatal nicotine exposure as a factor for RD and poor reading performance. Using smoking questionnaire and language data from the Avon Longitudinal Study of Parents and Children, we first det...
متن کاملFamily-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
BACKGROUND There is an extensive and inconsistent literature on the association of the dopamine D2 receptor gene (DRD2) with alcohol dependence. Conflicting results have been attributed to differences in the severity of the alcohol dependence phenotype across studies, failure to exclude related disorders from comparison groups, and artifacts of population-stratification. Recently the genetic po...
متن کاملImpulsivity-related cognition in alcohol dependence: Is it moderated by DRD2/ANKK1 gene status and executive dysfunction?
Perceived impaired control over alcohol use is a key cognitive construct in alcohol dependence that has been related prospectively to treatment outcome and may mediate the risk for problem drinking conveyed by impulsivity in non-dependent drinkers. The aim of the current study was to investigate whether perceived impaired control may mediate the association between impulsivity-related measures ...
متن کاملThe ANKK1/DRD2 locus is a genomic substrate for affective priming and recognition of angry faces.
INTRODUCTION Ankyrin repeat and kinase domain containing I (ANKK1) and dopamine D2 receptor (DRD2) genes have been associated with psychopathic traits in clinical samples. On the other hand, individuals high in psychopathy show reduced affective priming and deficits in facial expression recognition. We have hypothesized that these emotion-related cognitive phenomena are associated with Taq IA (...
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ژورنال
عنوان ژورنال: Psychiatry Research
سال: 2012
ISSN: 0165-1781
DOI: 10.1016/j.psychres.2011.09.024